| Range |
mouse L cell 2.1%: rabbit erythroid cell 3.5% (of which globin transcripts represent ≥85%) %
|
| Organism |
Mammals |
| Reference |
Jackson DA, Pombo A, Iborra F. The balance sheet for transcription: an analysis of nuclear RNA metabolism in mammalian cells. FASEB J. 2000 Feb14(2):242-54. p.243 right column 2nd paragraphPubMed ID10657981
|
| Primary Source |
[28] Brandhorst, B. P., and McConkey, E. H. (1974) Stability of nuclear RNA in mammalian cells. J. Mol. Biol. 85, 451–463 [29] Hunt, J. A. (1976) Ribonucleic acid synthesis in rabbit erythroid cells. Biochem J. 160, 727–744PubMed ID22003578, 1016252
|
| Method |
"Kinetic analyses of the entry of [3H]adenosine into
ATP and RNA establish levels of RNA synthesis
within intact cells." |
| Comments |
"At the same time, this approach [see measurement method] allows the proportion
of labeled RNA entering the cytoplasm to be
established. Only 2.1% hnRNA reaches the cytoplasm
as mRNA in mouse L cells (primary source 28), similar to the
3.5% seen for rabbit erythroid cells (primary source 29), where
globin transcripts represent at least 85% of cytoplasmic
mRNA." |
| Entered by |
Uri M |
| ID |
111162 |