Number of Phe-Gly (FG) nups (nucleoporins) that line the walls of the transport channel in each nuclear pore complex (NPC)
| Range | ~160 FG nups/NPC |
|---|---|
| Organism | Budding yeast Saccharomyces cerevisiae |
| Reference | Oeffinger M, Zenklusen D. To the pore and through the pore: a story of mRNA export kinetics. Biochim Biophys Acta. 2012 Jun1819(6):494-506. doi: 10.1016/j.bbagrm.2012.02.011. p.499 right column top paragraphPubMed ID22387213 |
| Primary Source | 88) F. Alber, S. Dokudovskaya, L.M. Veenhoff, W. Zhang, J. Kipper, D. Devos, et al., The molecular architecture of the nuclear pore complex, Nature 450 (2007) 695–701. (89) M. Rout, J. Aitchison, A. Suprapto, K. Hjertaas, Y. Zhao, B. Chait, The yeast nuclear pore complex: composition, architecture, and transport mechanism, J. Cell Biol. 148 (2000) 635–651.PubMed ID18046406, 10684247 |
| Comments | "In yeast, it has been shown that around 160 individual FG nups line the walls of the transport channel in each nuclear pore [primary sources]. FG nups are anchored to the core scaffold by the linker nups." |
| Entered by | Uri M |
| ID | 110676 |