Resting potential of dorsal root ganglion (DRG) neuron

Range -42 to -62 mV
Organism Rat Rattus norvegicus
Reference Chi X, Amet T, Byrd D, Chang KH, Shah K, Hu N, Grantham A, Hu S, Duan J, Tao F, Nicol G, Yu Q. Direct effects of HIV-1 Tat on excitability and survival of primary dorsal root ganglion neurons: possible contribution to HIV-1-associated pain. PLoS One. 2011 6(9):e24412. doi: 10.1371/journal.pone.0024412 p.2 right column bottom paragraphPubMed ID21912693
Method "To assess the excitability, the DRG neurons were held at their resting potentials (range between -42 and -62 mV), and a ramp of depolarizing current (1 s in duration) was applied to the neuron wherein the amplitude of the ramp was adjusted to produce three to four action potentials (APs) under control conditions."
Entered by Uri M
ID 106955