Volume of marker taken up by a dendritic cell

Range 1000-1500 µm^3
Organism Human Homo sapiens
Reference Sallusto F, Cella M, Danieli C, Lanzavecchia A. Dendritic cells use macropinocytosis and the mannose receptor to concentrate macromolecules in the major histocompatibility complex class II compartment: downregulation by cytokines and bacterial products. J Exp Med. 1995 Aug 1182(2):pp. 393 table 2PubMed ID7629501
Method Fluid phase uptake was measured using LY or FITC-DX in the presence of inhibitory concentrations of mannan.
Comments These volumes, which are probably underestimated because of losses, are close to the volume of the cell itself.
Entered by Uri M
ID 102635