Time to replicate the chromosome in exponentially growing E. coli Br as a function of growth rate at 37° celsius

Range 42-67 Table - link Minutes
Organism Bacteria Escherichia coli
Reference Neidhardt, F.C. et al. (1996) Escherichia coli and Salmonella typhimurium: Cellular and Molecular Biology, 2nd ed. chapter 97,
Comments C, time to replicate chromosome, in range depends on division rate. C=42 min for doubling time of 24 min. C=67 min for doubling time of 100 min. See note v under table. The seeming paradox of chromosome replication time being longer than doubling time is resolved by the observation that E. coli under ideal conditions employs nested replication forks that begin replicating the granddaughter cells while the daughter cells are still engaged in replication. Note in table that at doubling time between 60-100 min there should be a point where doubling time is about equal to chromosome replication time, yet they start at different points in time, as can be seen by the D period. See BNID 105035
Entered by Ron Milo - Admin
ID 100090