Fraction of genes that seem to coexist with their nearly identical duplicates (Incidence of gene duplication)

Range 1 - 10 %
Organism Eukaryotes
Reference Soskine M, Tawfik DS. Mutational effects and the evolution of new protein functions. Nat Rev Genet. 2010 Aug11(8):572-82. doi: 10.1038/nrg2808. p.577 right column bottom paragraphPubMed ID20634811
Primary Source Lynch, M. Genomics. Gene duplication and evolution. Science 297, 945–947 (2002).PubMed ID12169715
Comments "Divergence can occur through duplication of the ancestral gene to give two related genes, or ‘paralogues’ (genA and genB FIG. 3). Duplication is a very frequent event. This is apparent in a variety of eukaryotic genomes in which 1–10% of genes seem to coexist with their nearly identical duplicates (primary source) and by the high variability of gene copy number between individual genomes (refs 59,60). The duplicated segments span from several bases up to whole genomes."
Entered by Uri M
ID 110451