Direct sequencing estimates of mutation rates in mitochondrion (point mutations)

Value 9.7E-08 mutations/site/generation Range: Table - link mutations/site/generation
Organism Nematode Caenorhabditis elegans
Reference Kondrashov FA, Kondrashov AS. Measurements of spontaneous rates of mutations in the recent past and the near future. Philos Trans R Soc Lond B Biol Sci. 2010 Apr 27 365(1544):1169-76. doi: 10.1098/rstb.2009.0286. p.1172 table 1PubMed ID20308091
Primary Source Denver, D. R., Morris, K., Lynch, M., Vassilieva, L. L. & Thomas,W. K. 2000 High direct estimate of the mutation rate in the mitochondrial genome of Caenorhabditis elegans. Science 289, 2342–2344. (doi:10.1126/science. 289.5488.2342)PubMed ID11009418
Method "As far as quantitative estimates of mutation rate are concerned, a large fraction of them have been obtained in recent studies that use a multigeneration direct sequencing approach (table 1)."
Comments See "comments" column.
Entered by Uri M
ID 109997