Abundance of proteins in cell

Range <100 of many receptors: 1,000-10,000 signaling enzymes: 10^8 of some structural proteins Copies/cell
Organism Mammals
Reference Christopher E. Sims and Nancy L. Allbritton. Analysis of single mammalian cells on-chip, Lab Chip, 2007, 7, 423 - 440, DOI: 10.1039/b615235j p.425 left column top paragraphPubMed ID17389958
Primary Source Molecular Cell Biology, ed. H. Lodish, A. Berk, L. S. Zipursky, P. Matsudaira, D. Baltimore and J. Darnell, W. H. Freeman, New York, 4th edn, 2000. AND The Cell, ed. G. M. Cooper and R. E. Hausman, ASM Press, Washington, D.C., 4th edn, 2007.
Comments It is estimated that each cell may contain more than 100,000 different proteins having a wide disparity in abundance with <100 molecules of many receptors, 1,000–10,000 molecules for various signaling enzymes, and 10^8 molecules of some structural proteins.
Entered by Uri M
ID 106739