Number of capsid proteins in FHV

Value 180 Unitless
Organism Flock house virus (FHV)
Reference Baker TS, Olson NH, Fuller SD. Adding the third dimension to virus life cycles: three-dimensional reconstruction of icosahedral viruses from cryo-electron micrographs. Microbiol Mol Biol Rev. 1999 Dec63(4):862-922PubMed ID10585969
Primary Source Cheng RH, Reddy VS, Olson NH, Fisher AJ, Baker TS, Johnson JE. Functional implications of quasi-equivalence in a T = 3 icosahedral animal virus established by cryo-electron microscopy and X-ray crystallography. Structure. 1994 Apr 15 2(4):271-82.PubMed ID8087554
Method Cryo-electron microscopy and three-dimensional image reconstruction
Comments FHV (Nodaviridae family) has a T53 capsid consisting of 180 copies of a single, 44-kDa protein (407 aa) which encapsidates an ssRNA genome (three genes on two RNA molecules) (Fig. 26). The capsid proteins undergo a postassembly cleavage required for infectivity. This cleavage produces 180 gamma peptides (C-terminal 44 aa) on the interior of the virus.
Entered by Uri M
ID 104968