Diameter of insulin receptor

Value 6.51 nm
Organism Human Homo sapiens
Reference Parang K, Till JH, Ablooglu AJ, Kohanski RA, Hubbard SR, Cole PA. Mechanism-based design of a protein kinase inhibitor. Nat Struct Biol. 2001 Jan8(1):37-41.PubMed ID11135668
Primary Source pdb 1gag- link
Method Tris-phosphorylated cIRK (residues 978-1283) was prepared and structure determined by X ray diffraction. Measuring a line from amino acids Ser 981 to Asn 1233 on pdb 1gag (jmol image)
Comments Value is diameter of complex between insulin receptor (cIRK) and the bisubstrate inhibitor.
Entered by Uri M
ID 103212