Dopamine concentration causing half-maximal increase in activity of adenylate cyclase

Value 4 μM
Organism Rat Rattus norvegicus
Reference Kebabian JW, Petzold GL, Greengard P. Dopamine-sensitive adenylate cyclase in caudate nucleus of rat brain, and its similarity to the "dopamine receptor". Proc Natl Acad Sci U S A. 1972 Aug69(8):2145-9.PubMed ID4403305
Method The caudate nuclei of decapitated male rat brains were pooled and were homogenized in about 25 volumes (weight to volume) of 2 mM tris-(hydroxymethyl) aminomethane-maleate buffer (pH 7.4)-2 mM EGTA
Entered by Uri M
ID 102682