Volume of cardiomyocyte

Range 15.6±0.5х10^3 μm^3
Organism Rat Rattus norvegicus
Reference Calvillo L, Latini R, Kajstura J, Leri A, Anversa P, Ghezzi P, Salio M, Cerami A, Brines M. Recombinant human erythropoietin protects the myocardium from ischemia-reperfusion injury and promotes beneficial remodeling. Proc Natl Acad Sci U S A. 2003 Apr 15 100(8):4802-6. p.4805 left column top paragraphPubMed ID12663857
Method Abstract:"[Investigators] have assessed the potential protective role of EPO [Erythropoietin] in vitro with adult rat cardiomyocytes, and in vivo in a rat model of myocardial infarction with reperfusion."
Comments P.4805 left column top paragraph: "...cardiomyocyte volume normalized for nuclear density increased nearly 3-fold in the vehicle group (15.6±0.5×10^3µm^3 in sham to 45.0±0.6×10^3µm^3 in vehicle) but less than twice (27.0±0.2×10^3µm^3 P<0.05 vs. vehicle) in the rhEPO [recombinant human erythropoietin] group." The myocyte data in this paper is for Male Sprague–Dawley rats
Entered by Uri M
ID 108243