concentration of neostriatal dopamine in rats that received 6-hydroxy dopamine lesions

Value 2.14 ng/mg wet tissue Range: +-0.5 ng/mg wet tissue
Organism Rat Rattus norvegicus
Reference Berridge KC, Robinson TE. What is the role of dopamine in reward: hedonic impact, reward learning, or incentive salience? Brain Res Brain Res Rev. 1998 Dec28(3):309-69PubMed ID9858756
Method In a study of the consequences of dopamine loss, rats were depleted of dopamine in the nucleus accumbens and neostriatum by up to 99% using 6-hydroxydopamine. Sprague–Dawley rats were anesthetized with ketamine and Rompun
Comments The value is the average between the neostriatum (1.09+-0.58 ng/mg) and nucleus accumbens (2.19+-0.49 ng/mg)
Entered by Uri M
ID 102685