| Value |
1.46
kb/min
Range: ±0.01 (0.14 - 11.8) Table - link kb/min
|
| Organism |
Human Homo sapiens |
| Reference |
Conti C, Saccà B, Herrick J, Lalou C, Pommier Y, Bensimon A. Replication fork velocities at adjacent replication origins are coordinately modified during DNA replication in human cells. Mol Biol Cell. 2007 Aug18(8):3059-67. p.3062 table 1 & right column top paragraphPubMed ID17522385
|
| Method |
"[Researchers] examined human primary keratinocytes obtained from
skin biopsies carried out on three different donors and
grown with three different media conditions." |
| Comments |
"As shown in Figure 1D, measurements of
IdU and CldU signals revealed a mean fork velocity of
1.46±0.01 kb/min (Table 1), in agreement with previous
reports (Yurov, 1980 Jackson and Pombo, 1998). Noticeably,
a large heterogeneity in fork velocity was also observed,
with values ranging from 0.14 to 11.8 kb/min (panel in
Figure 1D)." See notes beneath table |
| Entered by |
Uri M |
| ID |
111200 |