Expected unpolymerized actin monomer concentration

Range ~40 µM
Organism Fission yeast Schizosaccharomyces pombe
Reference Berro J, Sirotkin V, Pollard TD. Mathematical modeling of endocytic actin patch kinetics in fission yeast: disassembly requires release of actin filament fragments. Mol Biol Cell. 2010 Aug 15 21(16):2905-15. doi: 10.1091/mbc.E10-06-0494. p.2910 right column top paragraphPubMed ID20587776
Comments "In wild-type cells the unpolymerized actin monomer concentration is expected to be ~40µM, so the filaments should grow twice as fast and the total polymerized actin per patch is expected to be about twofold higher than in mGFP-act1/act1+ diploids (Figure S1). This difference has a modest effect on the other reactions in the model."
Entered by Uri M
ID 111091