| Range |
~40 %
|
| Organism |
macaque |
| Reference |
Josselyn SA, Frankland PW. Infantile amnesia: a neurogenic hypothesis. Learn Mem. 2012 Aug 16 19(9):423-33. doi: 10.1101/lm.021311.110 p.427 left column 2nd paragraphPubMed ID22904373
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| Primary Source |
Jabès A, Lavenex PB, Amaral DG, Lavenex P. Quantitative analysis of postnatal neurogenesis and neuron number in the macaque monkey dentate gyrus. Eur J Neurosci. 2010 Jan31(2):273-85. doi: 10.1111/j.1460-9568.2009.07061.xPubMed ID20074220
|
| Method |
Primary source abstract: "[Investigators] performed design-based, stereological studies of neuron number and size, and volume of the dentate gyrus layers in rhesus macaque monkeys (Macaca mulatta) of different postnatal ages." |
| Comments |
P.427 left column 2nd paragraph: "Given the differences in lifespan between monkeys and rats (the lifespan of a monkey is ∼20–30 yr compared to 2–3 yr for rats), the overall contribution of postnatal neurogenesis in these two species is remarkably similar. Indeed, Jabès and colleagues estimate that ∼40% of neurons are added to the monkey DG after birth. Together, these data suggest that postnatal neurogenesis could have a substantial impact on hippocampal circuit function in rodents and primates, including humans." Primary source abstract: "[Investigators] found that about 40% of the total number of granule cells observed in mature 5-10-year-old macaque monkeys are added to the granule cell layer postnatally: 25% of these neurons are added within the first three postnatal months." |
| Entered by |
Uri M |
| ID |
117227 |