Unitary conductance of Panx1 (Pannexin1) hemichannels (Pannexins are vertebrate proteins identified by their homology to the invertebrate innexins)

Range ~500 pS
Organism
Reference Barbe MT, Monyer H, Bruzzone R. Cell-cell communication beyond connexins: the pannexin channels. Physiology (Bethesda). 2006 Apr21 :103-14 DOI: 10.1152/physiol.00048.2005 p.107 left column 2nd paragraphPubMed ID16565476
Primary Source [2] Bao L, Locovei S, Dahl G. Pannexin membrane channels are mechanosensitive conduits for ATP. FEBS Lett. 2004 Aug 13 572(1-3):65-8 DOI: 10.1016/j.febslet.2004.07.009PubMed ID15304325
Comments P.107 left column 2nd paragraph: "Panx1 hemichannels have a large unitary conductance of ~500 pS, and at least four substates (with 5%, 25%, 30%, and 90% of the maximal conductance) have been observed in single channel recordings (primary source)."
Entered by Uri M
ID 117158