Number of homeobox genes usually found in fungi and single-cell organisms and in Acanthamoeba

Range usually found in fungi and single-cell organisms <12: in Acanthamoeba 25 genes
Organism Various
Reference Bürglin TR, Affolter M. Homeodomain proteins: an update. Chromosoma. 2016 Jun125(3):497-521. doi: 10.1007/s00412-015-0543-8 p.498 left column 3rd paragraphPubMed ID26464018
Primary Source Derelle R, Lopez P, Le Guyader H, Manuel M. Homeodomain proteins belong to the ancestral molecular toolkit of eukaryotes. Evol Dev. 2007 May-Jun9(3):212-9 DOI: 10.1111/j.1525-142X.2007.00153.x AND Clarke M et al., Genome of Acanthamoeba castellanii highlights extensive lateral gene transfer and early evolution of tyrosine kinase signaling. Genome Biol. 2013 Feb 1 14(2):R11. doi: 10.1186/gb-2013-14-2-r11PubMed ID17501745, 23375108
Method Primary source Derelle et al., 2007 abstract: "Taking advantage from the recent burst of sequence data from a wide variety of eukaryote taxa, [investigators] show here that HD (Homeodomain)-containing transcription factors were already existing and diversified (in at least two main classes) in the last common eukaryote ancestor." Primary source Clarke et al., 2013 abstract: "Here [investigators] present an analysis of a whole genome assembly of Acanthamoeba castellanii (Ac) the first representative from a solitary free-living amoebozoan."
Comments P.498 left column 3rd paragraph: "In fungi and single-cell organisms, the number tends to be small, usually less than a dozen (primary source Derelle et al. 2007), but in Acanthamoeba, the homeobox family has expanded to 25 (primary source Clarke et al. 2013)."
Entered by Uri M
ID 116971