Number of genes that have >1 molecule of elongating RNA pol II/gene

Value <=1 Gene
Organism Budding yeast Saccharomyces cerevisiae
Reference Pelechano V, Chávez S, Pérez-Ortín JE. A complete set of nascent transcription rates for yeast genes. PLoS One. 2010 Nov 16 5(11):e15442. p.7 right column 2nd paragraphPubMed ID21103382
Method Researchers developed genomic variants of the well-known run-on technique to evaluate the nascent TR (transcription rate) for most genes. In this technique (GRO, Genomic Run-on), elongating RNA pol molecules, that conserve the RNA, are forced to incorporate radioactive UTP for a short length.
Comments The statistical distribution shows that less than 1% of yeast genes have >1 molecule of elongating RNA pol II/gene.
Entered by Uri M
ID 106769