Fraction of all germ cells in testes that are spermatogonial stem cells (SSCs)
| Range | 0.02%–0.03 % |
|---|---|
| Organism | Unspecified |
| Reference | Tanaka T et al., The Luteinizing Hormone-Testosterone Pathway Regulates Mouse Spermatogonial Stem Cell Self-Renewal by Suppressing WNT5A Expression in Sertoli Cells. Stem Cell Reports. 2016 Aug 9 7(2):279-91. doi: 10.1016/j.stemcr.2016.07.005 p.279 left column top paragraphPubMed ID27509137 |
| Comments | P.279 left column top paragraph: "Spermatogonial stem cells (SSCs) are the founder cell population of spermatogenesis (de Rooij and Russell, 2000, Meistrich and van Beek, 1993). Although their number in testes is very small (0.02%–0.03% of total germ cells), they are the only stem cells in the germline that have the unique ability to undergo self-renewal division to produce numerous progenitor cells." |
| Entered by | Uri M |
| ID | 115310 |