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P.1331 middle column bottom paragraph: "This theoretical example is not very different from what occurs on Earth with respect to the etiology of the most common form of lung cancer, adenocarcinoma. Epidemiologic studies have estimated that nearly 90% of adenocarcinomas of the lung are preventable and that tobacco smoke is by far the major component of E (environmental factors). Secondhand smoking, occupational exposures, ionizing radiation, air pollution, and diet play important but smaller roles (primary source 17, ref 18). Moreover, no hereditary factors have been implicated in lung adenocarcinomas (ref 19)." P.1331 right column top paragraph: "Thus, Cancer Research UK estimates that the great majority (89%) of lung adenocarcinoma cases are preventable (primary source), but even so, more than a third (35%) of the driver gene mutations in lung cancers can be attributed to R." |