| Range |
diameter 10-15µm: total protein per cell 64±14 - 95±25pg
|
| Organism |
Mammals |
| Reference |
Wiśniewski JR, Hein MY, Cox J, Mann M. A "proteomic ruler" for protein copy number and concentration estimation without spike-in standards. Mol Cell Proteomics. 2014 Dec13(12):3497-506. doi: 10.1074/mcp.M113.037309. p.3502 right column bottom paragraphPubMed ID25225357
|
| Primary Source |
[37] Dumortier H., van Mierlo G. J., Egan D., van Ewijk W., Toes R. E., Offringa R., Melief C. J. (2005) Antigen presentation by an immature myeloid dendritic cell line does not cause CTL deletion in vivo, but generates CD8+ central memory-like T cells that can be rescued for full effector function. J. Immunol. 175, 855–863PubMed ID16002683
|
| Comments |
P.3502 right column bottom paragraph: "Mature dendritic cells have diameters between 10 and 15 μm (primary source). [Investigators] compared these cell sizes to [their] proteomic ruler estimates that ranged between 64 ± 14 and 95 ± 25 pg total protein per cell for the different dendritic cell subtypes (Fig. 3D). These values translated to diameters of 8.5 to 9.7 μm for spherical cell shapes, which is expected to be slightly smaller than observed cell sizes, given the numerous dendrites projecting from the cell surfaces. Interestingly, [their] observed similarities in cell sizes correlate with overall patterns of proteomic similarity on the level of individual proteins that were observed in the original study (ref 36)." |
| Entered by |
Uri M |
| ID |
113239 |