Fraction of bacterial-like mitochondrial proteins that are not endosymbiotic in origin

Range ≤75 %
Organism Mitochondria
Reference Emelyanov VV. Mitochondrial connection to the origin of the eukaryotic cell. Eur J Biochem. 2003 Apr270(8):1599-618. p.1614 left column top paragraphPubMed ID12694174
Primary Source [13] Kurland, C.G. & Andersson, S.G.E. (2000) Origin and evolution of the mitochondrial proteome. Microbiol. Mol. Biol. Rev. 64, 786–820. [103] Karlberg, O., Canbäck, B., Kurland, C.G. & Andersson, S.G.E. (2000) The dual origin of the yeast mitochondrial proteome. Yeast 17, 170–187. DOI: 10.1002/1097-0061(20000930)17:3<170::AID-YEA25>3.0.CO2-VPubMed ID11104819, 11025528
Comments P.1613 left column bottom paragraph to p.1614 left column top paragraph: "In contrast, eukaryogenesis is hypothesised here (Fig. 1B, right panel) which is thought to be consistent with most phylogenetic data. Successive steps towards the construction of the eukaryotic cell are briefly summarized in Fig. 7. A primarily amitochondriate organism (pro-eukaryote) emerged as a true chimera [ref 23], with genetic apparatus acquired from an archaebacterium and core metabolism from a eubacterium. Bearing in mind the early origin of respiratory chains [refs 106,154], the bacterial fusion partner must have been a facultative anaerobe, e.g. similar to the γ-proteobacterium Escherichia coli, capable of oxidative phosphorylation. In effect, it could resemble a mitochondrial progenitor in many respects. Such a similarity may, in particular, account for the otherwise enigmatic fact that as many as 75% of bacterial-like mitochondrial proteins are not endosymbiotic in origin [primary sources]. Interestingly, this even pertains to some enzymes of the tricarboxylic acid cycle [primary source 13, refs 20,81]."
Entered by Uri M
ID 113208