| Comments |
P.136 left column 3rd paragraph: "The genome is a circular, single-stranded minus RNA enclosed in a particle (HDV virion) of between 35 and 41 nm in diameter, with no nuclocapsidic structure [primary source]. In the past, the circular conformation of the HDV-RNA was considered to be unique but recently several host-RNAs were found to be circular in conformation. The HDV-RNA genome is self-complementary, it folds into an unbranched rod structure with pairing of 70% of the nucleotides. Besides the 1.7 Kb genomic RNA contained in the virions, a complementary antigenomic RNA of positive polarity and a shorter polyadenilated mRNA of 0.8 Kb are present in the liver-their respective abundance per infected cell is about 300 000, 60 000 and 600 copies." |