Diversity of bacteria in Barrett’s oesophagus

Range Firmicutes 55%: Proteobacteria 20%: Bacteroidetes 14%: Fusobacteria 9%: Actinobacteria 2% %
Organism Human Homo sapiens
Reference Rubio CA. The Natural Antimicrobial Enzyme Lysozyme is Up-Regulated in Gastrointestinal Inflammatory Conditions. Pathogens. 2014 Jan 16 3(1):73-92. doi: 10.3390/pathogens3010073. p.75 bottom paragraphPubMed ID25437608
Primary Source [23] Liu N. et al., Characterization of bacterial biota in the distal esophagus of Japanese patients with reflux esophagitis and Barrett’s esophagus. BMC Infect. Dis. 2013, 13, 130–136. doi: 10.1186/1471-2334-13-130.PubMed ID23496929
Method P.75 bottom paragraph:"...analysis of 138 16S rDNA sequences from 240 clones of six cases of Barrett’s oesophagus..."
Comments P.75 bottom paragraph:"In a more recent study with oesophageal biopsies and aspirates, McFarlane et al. [ref 22] found in the mucosa of the Barrett’s oesophagus 46 bacterial species, belonging to 16 genera, with unique levels of Campylobacter consisus and C. rectus. Taken together, these microbiological findings denote a close association between the occurrence of columnar-lined oesophageal mucosa and the proliferation of abnormal bacteria in the oesophageal microenvironment. More recently, Liu et al. found Firmicutes (55%), Proteobacteria (20%), Bacteroidetes (14%), Fusobacteria (9%), and Actinobacteria (2%), in analysis of 138 16S rDNA sequences from 240 clones of six cases of Barrett’s oesophagus [primary source]."
Entered by Uri M
ID 112310