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Lumen negative transmucosal potential difference in healthy human colon in vivo and in vitro

Range	25 - 45 mV
Organism	Human Homo sapiens
Reference	Sandle GI. Salt and water absorption in the human colon: a modern appraisal. Gut. 1998 Aug43(2):294-9. p.294 right column top paragraphPubMed ID10189861
Primary Source	See refs in - link
Comments	"As the potential difference across the basolateral membrane (negatively charged with respect to the serosal surface) exceeds that across the apical membrane (negatively charged with respect to the luminal surface), a substantial lumen negative transmucosal potential difference (25–45 mV) is normally present in healthy human colon in vivo and in vitro, which largely reflects electrogenic Na+ transport (primary sources)."
Entered by	Uri M
ID	111316