| Range |
~50 different proteins
|
| Organism |
Yeast |
| Reference |
Vavylonis D, Wu JQ, Hao S, O'Shaughnessy B, Pollard TD. Assembly mechanism of the contractile ring for cytokinesis by fission yeast. Science. 2008 Jan 4 319(5859):97-100. p.97 left columnPubMed ID18079366
|
| Primary Source |
Guertin DA, Trautmann S, McCollum D. Cytokinesis in eukaryotes. Microbiol Mol Biol Rev. 2002 Jun66(2):155-78.PubMed ID12040122
|
| Comments |
"Cytokinesis is the final step in cell division,
when a dividing cell physically separates
into two. Assembly and constriction
of a contractile ring of actin, myosin, and associated
proteins cleaves cells in many organisms,
including animals and yeast. Analysis of
budding and fission yeast identified ~50 participating
proteins (primary source), the temporal sequence
of events (2), and local concentrations of many
proteins (3). A major challenge is to understand
how the network of proteins functions,
ultimately at the level of a testable quantitative
model of the entire system." |
| Entered by |
Uri M |
| ID |
111111 |