Range |
BSA=weight(kg)^0.425×height(cm)^0.725×0.007184
|
Organism |
Human Homo sapiens |
Reference |
Sacco JJ, Botten J, Macbeth F, Bagust A, Clark P. The average body surface area of adult cancer patients in the UK: a multicentre retrospective study. PLoS One. 2010 Jan 28 5(1):e8933. doi: 10.1371/journal.pone.0008933. p.1 left column bottom paragraphPubMed ID20126669
|
Primary Source |
DuBois D, DuBois EF (1916) A formula to estimate the approximate surface area if height and weight be known. Arch Internal Med 17: 863–871. |
Comments |
"The most widely used formula for BSA calculation is that devised by Du Bois and Du Bois in 1916. Plaster of Paris moulds of nine subjects were cut into small pieces in an attempt to measure
the two-dimensional surface area of the skin. Each individual’s body/skin surface area was then calculated and Du Bois and Du Bois determined that BSA was related to height and weight by the formula: weight(kg)^0.425×height(cm)^0.725×0.007184 [primary source]. Notably, this formula was derived from 9 subjects only, one of whom was a child. The age, sex and nutrition of these subjects, studied in the middle of the First World War, are unlikely to be
comparable to that of patients receiving chemotherapy in 2009. However, although several other formulae have since been put
forward [refs 8,9,10], none of these has gained widespread acceptance." |
Entered by |
Uri M |
ID |
111015 |