| Range |
guanine 5: hypoxanthine 50 nM
|
| Organism |
Bacteria Bacillus subtilis |
| Reference |
Batey RT, Gilbert SD, Montange RK. Structure of a natural guanine-responsive riboswitch complexed with the metabolite hypoxanthine. Nature. 2004 Nov 18 432(7015):411-5. doi:10.1038/nature03037 p.413 right column bottom paragraphPubMed ID15549109
|
| Primary Source |
Mandal, M., Boese, B., Barrick, J. E., Winkler, W. C. & Breaker, R. R. Riboswitches control fundamental biochemical pathways in Bacillus subtilis and other bacteria. Cell 113, 577–586 (2003).PubMed ID12787499
|
| Comments |
"In high Mg2+ ion concentrations (20 mM MgCl2), the guanine riboswitch has a very high affinity for guanine and hypoxanthine (an observed dissociation constant (Kd) of 5nM and 50nM, respectively, primary source)." |
| Entered by |
Uri M |
| ID |
110868 |