Glucosamine-6-phosphate binding constant to glmS ribozymes
| Range | 200 µM |
|---|---|
| Organism | Bacteria Bacillus subtilis |
| Reference | Winkler WC, Nahvi A, Roth A, Collins JA, Breaker RR. 2004. Control of gene expression by a natural metabolite-responsive ribozyme. Nature 428: 281–286. p.282 right column 2nd paragraph & p.283 left column 2nd paragraphPubMed ID15029187 |
| Comments | "The kinetic characteristics of the glmS ribozyme seem to be sufficient to serve as a riboswitch for the control of gene expression. A plot of the rate constant for ribozyme function versus the concentration of GlcN6P reveals that the rate constant for RNA cleavage becomes half maximal at a metabolite concentration of 200µM (Fig. 2c)." |
| Entered by | Uri M |
| ID | 110861 |