| Value |
7
pores/µm^2
Range: Table - link pores/µm^2
|
| Organism |
Mammalian tissue culture cell |
| Reference |
Mazzanti M, Bustamante JO, Oberleithner H. 2001. Electrical dimension of the nuclear envelope. Physiol. Rev. 81: 1–19 p.5 table 1 & p.11 right column top paragraphPubMed ID11152752
|
| Primary Source |
114) Oberleithner H, Brinckmann E, Schwab A, Krohne G. Imaging nuclear pores of aldosterone sensitive kidney cells by atomic force microscopy. Proc Natl Acad Sci USA 91: 9784–9788, 1994. (116) Oberleithner H1, Schneider S, Bustamante JO. Atomic force microscopy visualizes ATP-dependent dissociation of multimeric TATA-binding protein before translocation into the cell nucleus. Pflu¨ gers Arch 432: 839–844, 1996.PubMed ID7937891, 8772134
|
| Comments |
"Direct comparison of the data for the
different preparations reveals that GNE (total nuclear envelope conductance) varied by at least
a factor of 10. At first sight this is not very surprising since
NPC density per unit area can vary among different species
to a similar extent (refs 104, 144, 145). However, variations
in GNE occurred virtually independent of NPC density.
The NE of Chironomus salivary gland, for example,
showed a similar GNE per cm^2 (40 pores/µm^2) (refs 71, 125)
compared with GNE of cultured kidney cells (7 pores/µm^2) (primary sources)." See notes beneath table. MDCK=Madin Darby canine kidney |
| Entered by |
Uri M |
| ID |
110698 |