Elevation of intracellular Ca2+ in ciliary neuron following ATP depletion
Range | From 350 to 400 nM |
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Organism | Chicken Gallus gallus |
Reference | Bernstein BW, Bamburg JR. Actin-ATP hydrolysis is a major energy drain for neurons. J Neurosci. 2003 Jan 1 23(1):1-6. p.3 left column 2nd paragraphPubMed ID12514193 |
Comments | "In ciliary neurons, ATP depletion elevates [Ca2+]i from 350 to 400 nM (Fig. 4a), an increase that is six times less than that elicited by 1 mM caffeine (from 350 to 645 nM) (Jha et al., 2002). Because the [Ca2+]i increase elicited by 1 mM caffeine has no effect on MgGr [Magnesium green] intensity (data not shown), the far smaller [Ca2+]i increase caused by ATP depletion should not affect MgGr intensity either." |
Entered by | Uri M |
ID | 110640 |