| Value |
7
hours
|
| Organism |
Mammalian tissue culture cell |
| Reference |
Bishop WR, Bell RM. Assembly of phospholipids into cellular membranes: biosynthesis, transmembrane movement and intracellular translocation. Annu Rev Cell Biol. 1988 4: 579-610. p.600 bottom paragraphPubMed ID3058167
|
| Primary Source |
Voelker, D. R. 1985. Disruption of phos phatidylserine translocation to the mito chondria in baby hamster kidney cells. J. Bioi. Chern. 260: 14671-76PubMed ID2997219
|
| Comments |
"Voelker (primary source) examined transport of PS from ER to mitochondria
baby hamster kidney cells by exploiting the fact that PS synthesis occurs
in the ER and PS decarboxylase is a mitochondrial enzyme. Therefore,
labeling of PE with [3H]serine can be used to measure PS transport.
Transport of PS to the mitochondria (half-time of 7 h) was inhibited
treatment with NaN3 plus NaF, which suggests that transport is dependent
on ATP (primary source)." |
| Entered by |
Uri M |
| ID |
110383 |