---

Fidelity of HIV-1 and AMV reverse transcriptases and cellular DNA polymerases in a base subsitution reversion assay

Range	Table - link
Organism	Various
Reference	Roberts JD, Bebenek K, Kunkel TA. The accuracy of reverse transcriptase from HIV-1. Science. 1988 Nov 25 242(4882):1171-3. p.1172 table 1PubMed ID2460925
Method	See note above table
Comments	"HIV-1 RT generated revertants at a frequency of 100x10^-6 (Table 1). This is more than 50 times above the spontaneous background reversion frequency of uncopied DNA, showing that errors are indeed the result of DNA polymerization in vitro." AMV=avian myeloblastosis virus
Entered by	Uri M
ID	110132