Bioinformatic analysis of phosphorylation-dependent protein turnover in HeLa cell and C2C12 mouse cells
| Range | Table - link hour^-1 |
|---|---|
| Organism | Mammals |
| Reference | Cambridge SB, Gnad F, Nguyen C, Bermejo JL, Krüger M, Mann M. Systems-wide proteomic analysis in mammalian cells reveals conserved, functional protein turnover. J Proteome Res. 2011 Dec 2 10(12):5275-84. doi: 10.1021/pr101183k. Supporting info p.4 Suppl Table 2PubMed ID22050367 |
| Method | Stable isotope labeling in cell culture (SILAC) |
| Comments | "Proteins were grouped according to 33 well-characterized kinase motifs and the corresponding kdeg values (proteins with a particular kinase motif versus all others) pairwise analyzed with a student’s T-Test. In the kinase sequences, ‘.’ can be any amino acid and brackets [] denote all possible amino acids at this position." |
| Entered by | Uri M |
| ID | 109744 |