Range |
-0.34 V
|
Organism |
Cow Bos Taurus |
Reference |
Hirst J. Mitochondrial complex I. Annu Rev Biochem. 2013 Jun 2 82 :551-75. doi: 10.1146/annurev-biochem-070511-103700. p.557 left column bottom paragraphPubMed ID23527692
|
Primary Source |
Zu Y, Shannon RJ, Hirst J. Reversible, electrochemical interconversion of NADH and NAD+ by the catalytic (Ilambda) subcomplex of mitochondrial NADH:ubiquinone oxidoreductase (complex I). J Am Chem Soc. 2003 May 21 125(20):6020-1.PubMed ID12785808
|
Comments |
"The flavin in B. taurus complex I has an
unusually low reduction potential, -0.38 V at
pH7.5 (23), because the oxidized flavin is bound
more strongly than the reduced flavin. The reduction
potential of NAD+ is slightly higher
(-0.34 V) and NADH oxidation by complex I is
thermodynamically reversible (energy conserving)
(primary source)." |
Entered by |
Uri M |
ID |
109181 |