Number of DNA replication origins activated in each cell cycle

Range 30,000 to 50,000 origins/cycle
Organism Mammals
Reference Symeonidou IE, Taraviras S, Lygerou Z. Control over DNA replication in time and space. FEBS Lett. 2012 Aug 31 586(18):2803-12. doi: 10.1016/j.febslet.2012.07.042 p.2803 left column top paragraphPubMed ID22841721
Comments "Precise spatiotemporal regulation of DNA replication is crucial for the maintenance of genomic integrity. DNA replication in eukaryotic cells initiates from hundreds of sites along the genome, called origins of replication. In mammals, 30,000 to 50,000 origins are activated in each cell cycle."
Entered by Uri M
ID 108756