Number of copies of Ef-Tu, most abundant protein

Value 2300 copies/cell
Organism Bacteria Mycoplasma pneumoniae
Reference Maier T, Schmidt A, Güell M, Kühner S, Gavin AC, Aebersold R, Serrano L. Quantification of mRNA and protein and integration with protein turnover in a bacterium. Mol Syst Biol. 2011 Jul 19 7: 511. doi: 10.1038/msb.2011.38. p.2 left columnPubMed ID21772259
Method Mass spectrometry and Western blot validation: "...researchers measured individual protein levels in average copies per cell under control conditions (growth for 96 h), along a 4-day time course, in response to heat shock, DNA damage and osmotic stress (Supplementary Table S2)."
Comments "Cellular protein abundances span three orders of magnitude ranging from about 2300 copies (Ef-Tu) to two copies (uncharacterized protein MPN554 Supplementary Figure S1 Supplementary Table S2) with an average abundance of 167 copies per cell"
Entered by Uri M
ID 108336