Abundance of ribonucleoside-diphosphate reductase

Value 300 copies/cell
Organism Bacteria Mycoplasma pneumoniae
Reference Maier T, Schmidt A, Güell M, Kühner S, Gavin AC, Aebersold R, Serrano L. Quantification of mRNA and protein and integration with protein turnover in a bacterium. Mol Syst Biol. 2011 Jul 19 7: 511. doi: 10.1038/msb.2011.38. p.5 right column bottom paragraphPubMed ID21772259
Method Mass spectrometry and Western blot validation: "...researchers measured individual protein levels in average copies per cell under control conditions (growth for 96 h), along a 4-day time course, in response to heat shock, DNA damage and osmotic stress (Supplementary Table S2)."
Comments "For several well-characterized protein complexes, such as the GroEL/ES chaperonin (160 multimeric complexes per cell), DNA gyrase (50 A2B2 tetramers per cell) or ribonucleoside- diphosphate reductase (300 copies per cell), cellular abundances of the subunits reflect the expected complex stoichiometries closely (Figure 4B Supplementary Figure S13)."
Entered by Uri M
ID 108353