| Range |
0.8±0.5 obese individuals: 0.3±0.2 lean individuals х10^10 cells/year
|
| Organism |
Human Homo sapiens |
| Reference |
Spalding, KL et al. Dynamics of fat cell turnover in humans. Nature. May 2008. 453(7196):783-7. p.786 left column top paragraphPubMed ID18454136
|
| Method |
Researchers used a recently developed method that is based on
the incorporation of 14C from nuclear bomb tests into genomic DNA
and allows the analysis of cell turnover in humans. Using the death-rate estimates and the fat cell numbers calculated
for individual subjects, absolute fat cell production was calculated. |
| Comments |
Obese individuals were found to have a significantly greater number
of adipocytes added per year than lean individuals: (0.8±0.5)?10^10
cells per yr versus (0.3±0.2)?10^10 cells per yr (median±average
deviation P<0.01, ANOVA Fig. 4b). |
| Entered by |
Uri M |
| ID |
107878 |