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Highest lycopene yield

Value	9000 µg/g dry weight
Organism	Bacteria Escherichia coli
Reference	Wang HH et al., Programming cells by multiplex genome engineering and accelerated evolution. Nature. 2009 Aug 13 460(7257):894-8. p.896 right column 2nd paragraphPubMed ID19633652
Method	To demonstrate an application of the multiplex automated genome engineering process (MAGE), researchers optimized metabolic flux through the 1-deoxy-Dxylulose- 5-phosphate (DXP) biosynthesis pathway to overproduce the isoprenoid, lycopene, in an E. coli strain (EcHW2) that contained the pAC-LYC plasmid that is necessary for the final steps of lycopene production.
Comments	9,000 p.p.m
Entered by	Uri M
ID	106027