| Value |
5.8
unitless
|
| Organism |
Mammalian tissue culture cell |
| Reference |
Vazquez A. Optimal cytoplasmatic density and flux balance model under macromolecular crowding effects. J Theor Biol. 2010 May 21 264(2):356-9 p.357 left column 2nd paragraphPubMed ID20171231
|
| Primary Source |
Kao HP, Abney JR, Verkman AS. Determinants of the translational mobility of a small solute in cell cytoplasm. J Cell Biol. 1993 Jan120(1):175-84.PubMed ID8416987
|
| Method |
To quantify the impact of crowding on metabolites
diffusion the following empirical exponential law is used: ?D=e^-(a?) where the exponent a is an empirical parameter (? is viscosity). The closest estimate for the cytoplasm comes from the experimental report a=5.8 for fibroblast cells (swiss 3T3 mouse cells, primary source) |
| Comments |
Note-Ref gives value of 5.8 citing primary source. However primary source p.180 legend to fig. 6B gives value of 0.058 (and v=1.06) |
| Entered by |
Uri M |
| ID |
105816 |