mRNA elongation rate in embryo

Range 6-9 nts/sec
Organism Sea urchin Strongylocentrotus purpuratus
Reference Ben-Tabou de-Leon S, Davidson EH. Modeling the dynamics of transcriptional gene regulatory networks for animal development. Dev Biol. 2009 Jan 15 325(2):317-28 p. 318 right column 2nd paragraphPubMed ID19028486
Primary Source Aronson AI, Chen K. Rates of RNA chain growth in developing sea urchin embryos. Dev Biol. 1977 Aug59(1):39-48.PubMed ID892220
Method [Primary source abstract] One procedure involved quantitation of isolated nucleosides derived from the 3’ end of newly synthesized chains plus total rates of nucleotide incorporation. The former values provide the number of growing chains so that rates of incorporation per RNA chain may be calculated. A second procedure involves determinations of the times required for RNA molecules of given size classes to become fully labeled.
Comments In sea urchin (S. purpuratus) embryos that are cultured at 15 °C.
Entered by Uri M
ID 105618