| Comments |
The integration host factor of E. coli (IHF) is a
small dimeric protein that bends DNA at the
specific sequences to which it binds. It supports
several cellular reactions involving the formation of
higher-ordered structures, such as transposition,
initiation of DNA replication, and bacteriophage lambda
site-specific recombination. The rate of isomerization from the closed to the
open complex (kf) at pL is unaffected by IHF. This value is a product of kf (isomerization constant, 0.00438sec^-1, BNID 105128) and kB (RNAP binding constant, (8.94×10^7M^-1)). See BNID 105127 |