| Value |
2E-05
(Substitution/generation)^2
|
| Organism |
Fruit fly Drosophila melanogaster |
| Reference |
Landry CR, Lemos B, Rifkin SA, Dickinson WJ, Hartl DL. Genetic properties influencing the evolvability of gene expression. Science. 2007 Jul 6 317(5834):118-21PubMed ID17525304
|
| Primary Source |
Rifkin SA, Houle D, Kim J, White KP. A mutation accumulation assay reveals a broad capacity for rapid evolution of gene expression. Nature. 2005 Nov 10 438(7065):220-3PubMed ID16281035
|
| Method |
(Primary source): Researchers estimate the rate at which mutation produces new variation in gene expression by measuring transcript abundances across the genome during the onset of metamorphosis in 12 initially identical Drosophila melanogaster lines that independently accumulated mutations for 200 generations. |
| Comments |
The rate of phenotypic evolution due to
mutation alone can be measured by the mutational
variance (Vm), which is defined as the
increase in the variance of a trait introduced by
mutations each generation. It can be calculated
from the variance of traits among MA (Mutation Accumulation) lines. For
haploid asexual organisms, Vm = 2sb^2/t, where
sb^2 is the between-line variance and t is the
number of generations. See BNID 105090 |
| Entered by |
Uri M |
| ID |
105091 |