Haploid mutation rate

Value 0.052 1/genome/generation
Organism Fruit fly Drosophila melanogaster
Reference Joseph SB, Hall DW. Spontaneous mutations in diploid Saccharomyces cerevisiae: more beneficial than expected. Genetics. 2004 Dec168(4):1817-25 Table - link PubMed ID15611159
Primary Source Fry JD, Keightley PD, Heinsohn SL, Nuzhdin SV. New estimates of the rates and effects of mildly deleterious mutation in Drosophila melanogaster. Proc Natl Acad Sci U S A. 1999 Jan 1996(2):574-9PubMed ID9892675
Method Mutation accumulation studies. Three large homozygous control populations were maintained. Egg-to-adult viability of 72 nonlethal mutation-accumulation (MA) lines and the controls was assayed after 27-33 generations of mutation accumulation.
Comments The effect of mutations is measured in homozygotes
Entered by Uri M
ID 104472