Number of transcription factor genes

Value 1093 Unitless
Organism Nematode Caenorhabditis remanei
Reference Haerty W, Artieri C, Khezri N, Singh RS, Gupta BP. Comparative analysis of function and interaction of transcription factors in nematodes: extensive conservation of orthology coupled to rapid sequence evolution. BMC Genomics. 2008 Aug 27 9: 399 abstract, p.3 table 2, p.3 left column 2nd paragraph & p.10 left column bottom paragraphPubMed ID18752680
Method Abstract: "[Researchers] identified 988 TF [transcription factor] genes in C. elegans, and inferred corresponding sets in C. briggsae and C. remanei, containing 995 and 1093 TF genes, respectively. Analysis of the three gene sets revealed 652 3-way reciprocal 'best hit' orthologs (nematode TF set), approximately half of which are zinc finger (ZF-C2H2 and ZF-C4/NHR types) and HOX family members. Examination of the TF genes in C. elegans and C. briggsae identified the presence of significant tandem clustering on chromosome V, the majority of which belong to ZF-C4/NHR family."
Comments P.10 left column bottom paragraph: "This paper presents the first genome-wide comparative study of TF genes in nematodes and their orthologs in fly (D. melanogaster), mouse (M. musculus), and human (H. sapiens). [Researchers] took both computational and manual curation approaches to compile sets of TF genes in three Caenorhabditid species, leading to the identification of 988 genes in C. elegans, 995 in C. briggsae and 1093 in C. remanei." See BNID 105072, 105073
Entered by Uri M
ID 105074