| Range |
>1e+10 Cells/gram gut content
|
| Organism |
Human Homo sapiens |
| Reference |
Macfarlane GT, Macfarlane S, Gibson GR. Validation of a Three-Stage Compound Continuous Culture System for Investigating the Effect of Retention Time on the Ecology and Metabolism of Bacteria in the Human Colon. Microb Ecol. 1998 Mar35(2):180-7 p.183 fig.4 left column top row & p.186 left column 2nd paragraphPubMed ID9541554
|
| Method |
"[Researchers] developed a three-stage compound
continuous culture system that enables the activities of intestinal
bacteria to be studied under the low pH, carbohydrate-excess conditions that characterize the proximal colon,
as well as the carbohydrate-depleted, nonacidic environmemt
that is analogous to the distal bowel [refs 13, 19]." |
| Comments |
"Although several hundred different strains of bacteria can
be isolated from feces [ref 9], about 99% of all culturable organisms
belong to 30 or 40 species [ref 19]. In this study, measurements
using 9 groups of marker bacteria demonstrated
that high numbers of anaerobes were present in the large
intestine, exceeding 10^10 per gram of gut contents (Fig. 4). Species belonging to the genera Bifidobacterium and Bacteroides
predominated. The data also indicated that, with the
exception of bifidobacteria, bacterial populations varied little
in the proximal and distal bowels. These results suggest that,
while the generic composition of the colonic microbiota may
not change significantly as digestive material moves through
the gut, large variations do occur, with respect to its metabolic
activities, especially the fermentation of organic carbon
and nitrogen sources." For concentration of 10^10 bacteria/ml in Sheep rumen see BNID 102396. See BNID 104949 |
| Entered by |
Uri M |
| ID |
104948 |