Distance between the molecular motor kinesin and its cargo
| Value | 17 nm Range: ±2 nm |
|---|---|
| Organism | Eukaryotes |
| Reference | Kerssemakers J, Howard J, Hess H, et al., The distance that kinesin-1 holds its cargo from the microtubule surface measured by fluorescence interference contrast microscopy, PNAS 103: 15812 (2006)PubMed ID17035506 |
| Method | Measured in an in vitro gliding assay with nanometer precision via fluorescence interference contrast microscopy which is based on the self-interference of fluorescent light from objects near a reflecting surface. |
| Comments | More precisely: This is the distance that kinesin-1 elevates a gliding microtubule above the surface in a gliding assay. |
| Entered by | Melanie JI Muller |
| ID | 104883 |