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mRNA half-lives of Escherichia coli genes in degradosome mutant strains

Range	Table - link
Organism	Bacteria Escherichia coli
Reference	Bernstein JA, Lin PH, Cohen SN, Lin-Chao S. Global analysis of Escherichia coli RNA degradosome function using DNA microarrays. Proc Natl Acad Sci U S A. 2004 Mar 2 101(9):2758-63PubMed ID14981237
Method	To investigate the degradosome's proposed role as an RNA decay machine, researchers used DNA microarrays to globally assess alterations in the steady-state abundance and decay of 4,289 E. coli mRNAs at single-gene resolution in bacteria carrying mutations in the degradosome constituents RNase E, polynucleotide phosphorylase, RhlB helicase, and enolase.
Entered by	Uri M
ID	104322